API reference
Domperidone
- CAS number
- 57808-66-9
- Molecular formula
- C22H24ClN5O2
- Molecular weight
- 425.9 g/mol
About this molecule
Domperidone is 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations. It has a role as a dopaminergic antagonist and an antiemetic. It is a member of benzimidazoles and a heteroarylpiperidine.
Source: ChEBI, via PubChem.
Identifiers
- IUPAC name
- 6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1H-benzimidazol-2-one
- InChIKey
- FGXWKSZFVQUSTL-UHFFFAOYSA-N
- SMILES
- C1CN(CCC1N2C3=C(C=C(C=C3)Cl)NC2=O)CCCN4C5=CC=CC=C5NC4=O
- PubChem CID
- 3151
Also known as
domperidone · Motilium · Domperidona · Domperidonum · Domperidon · R 33,812 · Evoxin · Domilium
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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