API reference
DOXAPRAM HCl
- CAS number
- 7081-53-0
- Molecular formula
- C24H33ClN2O3
- Molecular weight
- 433 g/mol
About this molecule
Doxapram Hydrochloride is a peripheral and central respiratory stimulant with a brief duration of action. Doxapram hydrochloride stimulates respiration by an action on chemoreceptors in the carotid arteries and, at increased dosage, stimulates central respiratory centers in the medulla as well as other parts of the brain and spinal cord. This results in an increased tidal volume and a slightly increased respiratory rate. Doxapram hydrochloride may also improve cardiac output probably due to an increased release of catecholamines. This respiratory stimulant is used in postanesthesia respiratory depression.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 1-ethyl-4-(2-morpholin-4-ylethyl)-3,3-diphenylpyrrolidin-2-one;hydrate;hydrochloride
- InChIKey
- ZOMBFZRWMLIDPX-UHFFFAOYSA-N
- SMILES
- CCN1CC(C(C1=O)(C2=CC=CC=C2)C3=CC=CC=C3)CCN4CCOCC4.O.Cl
- Other CAS numbers recorded
- 15083-72-4
- PubChem CID
- 64648
Also known as
Doxapram hydrochloride monohydrate · Doxapram HCL · Stimulexin · AHR-619 · Doxapram Hydrochloride · Doxapram hydrochloride hydrate · Dopram · DoxapraM interMediate
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