API reference
DRONEDARONE HCl
- CAS number
- 141625-93-6
- Molecular formula
- C31H45ClN2O5S
- Molecular weight
- 593.2 g/mol
About this molecule
Dronedarone Hydrochloride is the hydrochloride salt form of dronedarone, an orally bioavailable benzofuran derivative, with anti-arrhythmic activity. Upon oral administration, and although the exact mechanism of action through which dronedarone exerts its anti-arrhythmic effect has not been fully elucidated, it inhibits multiple voltage-gated ion channels, including sodium, potassium, and calcium ion channels, and restores the normal sinus rhythm and reduces heart rate in atrial fibrillation. It also non-competitively antagonizes adrenergic receptors.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- N-[2-butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]-1-benzofuran-5-yl]methanesulfonamide;hydrochloride
- InChIKey
- DWKVCQXJYURSIQ-UHFFFAOYSA-N
- SMILES
- CCCCC1=C(C2=C(O1)C=CC(=C2)NS(=O)(=O)C)C(=O)C3=CC=C(C=C3)OCCCN(CCCC)CCCC.Cl
- PubChem CID
- 219025
Also known as
Dronedarone hydrochloride · Dronedarone HCl · DRONEDARONE HYDROCHLORIDE (MART.) · DRONEDARONE HYDROCHLORIDE (USP-RS) · DRONEDARONE HYDROCHLORIDE (EP MONOGRAPH) · DRONEDARONE HYDROCHLORIDE (USP MONOGRAPH) · Multaq · Dronedarone (Hydrochloride)
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