API reference
Droperidol
- CAS number
- 548-73-2
- Molecular formula
- C22H22FN3O2
- Molecular weight
- 379.4 g/mol
About this molecule
Droperidol is an organofluorine compound that is haloperidol in which the hydroxy group has been eliminated with the introduction of a double bond in the piperidine ring, and the 4-chlorophenyl group has been replaced by a benzimidazol-2-on-1-yl group. It is used in the management of chemotherapy-induced nausea and vomiting, and in conjunction with an opioid analgesic such as fentanyl to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon. It has a role as a dopaminergic antagonist, an antiemetic, an anaesthesia adjuvant and a first generation antipsychotic. It is a member of benzimidazoles, an organofluorine compound and an aromatic ketone.
Source: ChEBI, via PubChem.
Identifiers
- IUPAC name
- 3-[1-[4-(4-fluorophenyl)-4-oxobutyl]-3,6-dihydro-2H-pyridin-4-yl]-1H-benzimidazol-2-one
- InChIKey
- RMEDXOLNCUSCGS-UHFFFAOYSA-N
- SMILES
- C1CN(CC=C1N2C3=CC=CC=C3NC2=O)CCCC(=O)C4=CC=C(C=C4)F
- PubChem CID
- 3168
Also known as
droperidol · Droleptan · Dehydrobenzperidol · Inapsine · Dridol · Inapsin · Properidol · Sintodril
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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