API reference
DULOXETINE HCl
- CAS number
- 136434-34-9
- Molecular formula
- C18H20ClNOS
- Molecular weight
- 333.9 g/mol
About this molecule
Duloxetine (brand names Cymbalta, Yentreve, and in parts of Europe, Xeristar or Ariclaim) is a drug which primarily targets major depressive disorder (MDD), generalized anxiety disorder (GAD), pain related to diabetic peripheral neuropathy and in some countries stress urinary incontinence (SUI). It is manufactured and marketed by Eli Lilly and Company. Duloxetine has not yet been FDA approved for stress urinary incontinence or for fibromyalgia. Duloxetine is a selective SNRI (selective serotonin-norepinephrine reuptake inhibitor). Duloxetine is a systemic drug therapy which affects the body as a whole. Known also under the code name LY248686, it is a potent dual reuptake inhibitor of serotonin (5-hydroxytryptamine, 5-HT) and norepinephrine (NE), possessing comparable affinities in binding to NE- and 5-HT transporter sites. It is a less potent inhibitor of dopamine reuptake.
Source: Toxin and Toxin Target Database (T3DB), via PubChem.
Identifiers
- IUPAC name
- (3S)-N-methyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine;hydrochloride
- InChIKey
- BFFSMCNJSOPUAY-LMOVPXPDSA-N
- SMILES
- CNCC[C@@H](C1=CC=CS1)OC2=CC=CC3=CC=CC=C32.Cl
- Other CAS numbers recorded
- 947316-47-4
- PubChem CID
- 60834
Also known as
DULOXETINE HYDROCHLORIDE · Duloxetine HCl · Ariclaim · Duloxetine mylan · Duloxetine (as hydrochloride) · Duloxetine Boehringer Ingelheim · Duloxicaine · Duciltia
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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