API reference
Econazole nitrate
- CAS number
- 24169-02-6
- Molecular formula
- C18H16Cl3N3O4
- Molecular weight
- 444.7 g/mol
About this molecule
Econazole is only found in individuals that have used or taken this drug. It is a broad spectrum antimycotic with some action against Gram positive bacteria. It is used topically in dermatomycoses also orally and parenterally. [PubChem] Econazole interacts with 14-alpha demethylase, a cytochrome P-450 enzyme necessary to convert lanosterol to ergosterol. As ergosterol is an essential component of the fungal cell membrane, inhibition of its synthesis results in increased cellular permeability causing leakage of cellular contents. Econazole may also inhibit endogenous respiration, interact with membrane phospholipids, inhibit the transformation of yeasts to mycelial forms, inhibit purine uptake, and impair triglyceride and/or phospholipid biosynthesis.
Source: Toxin and Toxin Target Database (T3DB), via PubChem.
Identifiers
- IUPAC name
- 1-[2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole;nitric acid
- InChIKey
- DDXORDQKGIZAME-UHFFFAOYSA-N
- SMILES
- C1=CC(=CC=C1COC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl)Cl.[N+](=O)(O)[O-]
- Other CAS numbers recorded
- 68797-31-9
- PubChem CID
- 68589
Also known as
Econazole nitrate · Spectazole · Ifenec · Epi-pevaryl · Pevaryl · Gyno-Pevaryl 150 · Econazole mononitrate · (+-)-Econazole nitrate
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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