API reference
Efavirenz
- CAS number
- 154598-52-4
- Molecular formula
- C14H9ClF3NO2
- Molecular weight
- 315.67 g/mol
About this molecule
Efavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency virus (HIV) type 1. For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with zidovudine or tenofovir is the preferred NNRTI-based regimen. Efavirenz is also used in combination with other antiretroviral agents as part of an expanded postexposure prophylaxis regimen to prevent HIV transmission for those exposed to materials associated with a high risk for HIV transmission.
Source: DrugBank, via PubChem.
Identifiers
- IUPAC name
- (4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one
- InChIKey
- XPOQHMRABVBWPR-ZDUSSCGKSA-N
- SMILES
- C1CC1C#C[C@]2(C3=C(C=CC(=C3)Cl)NC(=O)O2)C(F)(F)F
- PubChem CID
- 64139
Also known as
efavirenz · Sustiva · Stocrin · DMP-266 · (-)-Efavirenz · Viraday · Efavirenz teva · Efavirenzum
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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