API reference
Emtricitabine
- CAS number
- 143491-57-0
- Molecular formula
- C8H10FN3O3S
- Molecular weight
- 247.25 g/mol
About this molecule
Emtricitabine is a synthetic fluoro derivative of thiacytidine with potent antiviral activity. Emtricitabine is phosphorylated to form emtricitabine 5'-triphosphate within the cell. This metabolite inhibits the activity of human immunodeficiency virus (HIV) reverse transcriptase both by competing with the natural substrate deoxycytidine 5'-triphosphate and by incorporation into viral DNA causing a termination of DNA chain elongation (due to the lack of the essential 3'-OH group).
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one
- InChIKey
- XQSPYNMVSIKCOC-NTSWFWBYSA-N
- SMILES
- C1[C@H](O[C@H](S1)CO)N2C=C(C(=NC2=O)N)F
- Other CAS numbers recorded
- 145213-48-5
- PubChem CID
- 60877
Also known as
Emtricitabine · Coviracil · Emtriva · 524W91 · dOTFC · BW-524W91 · 2-FTC · (-)-2'-Deoxy-5-fluoro-3'-thiacytidine
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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