API reference

Etoricoxib

CAS number
202409-33-4
Molecular formula
C18H15ClN2O2S
Molecular weight
358.8 g/mol
Etoricoxib — 2D structure
2D structure (PubChem)

About this molecule

Etoricoxib is a new COX-2 selective inhibitor. Current therapeutic indications are: treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout. Like any other COX-2 selective inhibitor, Etoricoxib selectively inhibits isoform 2 of cyclo-oxigenase enzyme (COX-2) to reduce the generation of prostaglandins (PGs) from arachidonic acid. It is approved in more than 60 countries worldwide but not in the US.

Source: DrugBank, via PubChem.

Identifiers

IUPAC name
5-chloro-2-(6-methyl-3-pyridinyl)-3-(4-methylsulfonylphenyl)pyridine
InChIKey
MNJVRJDLRVPLFE-UHFFFAOYSA-N
SMILES
CC1=NC=C(C=C1)C2=C(C=C(C=N2)Cl)C3=CC=C(C=C3)S(=O)(=O)C
PubChem CID
123619

Also known as

Etoricoxib · Arcoxia · etoricoxibum · M01AH05 · Nucoxia · Tauxib · Etoricoxibe · Kingcox

Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.

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