API reference
Etravirine
- CAS number
- 269055-15-4
- Molecular formula
- C20H15BrN6O
- Molecular weight
- 435.3 g/mol
About this molecule
Etravirine is an aminopyrimidine that consists of 2,6-diaminopyrimidine bearing a bromo substituent at position 5, a 4-cyano-2,6-dimethylphenoxy substituent at position 4 and having a 4-cyanophenyl substituent attached to the 2-amino group. NNRTI of HIV-1, binds directly to RT and blocks RNA-dependent and DNA-dependent DNA polymerase activities. It has a role as an antiviral agent and a HIV-1 reverse transcriptase inhibitor. It is an aromatic ether, an organobromine compound, an aminopyrimidine and a dinitrile.
Source: ChEBI, via PubChem.
Identifiers
- IUPAC name
- 4-[6-amino-5-bromo-2-(4-cyanoanilino)pyrimidin-4-yl]oxy-3,5-dimethylbenzonitrile
- InChIKey
- PYGWGZALEOIKDF-UHFFFAOYSA-N
- SMILES
- CC1=CC(=CC(=C1OC2=NC(=NC(=C2Br)N)NC3=CC=C(C=C3)C#N)C)C#N
- Other CAS numbers recorded
- 1142096-06-7 · 394729-17-0
- PubChem CID
- 193962
Also known as
Etravirine · Intelence · TMC-125 · TMC125 · TMC 125 · Etravirina · TMC125 cpd · etravirinum
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
Tell us the grade, the quantity and the market.
Send the molecule or ingredient, the specification and the destination. We reply from Tehran with the questions, the documents and the next step.