API reference
Famotidine
- CAS number
- 76824-35-6
- Molecular formula
- C8H15N7O2S3
- Molecular weight
- 337.5 g/mol
About this molecule
Famotidine is a competitive histamine-2 (H2) receptor antagonist that works to inhibit gastric acid secretion. It is commonly used in gastrointestinal conditions related to acid secretion, such as gastric ulcers and gastroesophageal reflux disease (GERD), in adults and children. Compared to other H2 receptor antagonists, famotidine displays high selectivity towards this receptor; in a study consisting of healthy volunteers and patients with acid hypersecretory disease, famotidine was about 20 to 50 times more potent at inhibiting gastric acid secretion than [cimetidine] and eight times more potent than [ranitidine] on a weight basis. Famotidine is used in various over-the-counter and off-label uses. While oral formulations of famotidine are more commonly used, the intravenous solution of the drug is available for use in hospital settings.
Source: DrugBank, via PubChem.
Identifiers
- IUPAC name
- 3-[[2-(diaminomethylideneamino)-1,3-thiazol-4-yl]methylsulfanyl]-N'-sulfamoylpropanimidamide
- InChIKey
- XUFQPHANEAPEMJ-UHFFFAOYSA-N
- SMILES
- C1=C(N=C(S1)N=C(N)N)CSCC/C(=N/S(=O)(=O)N)/N
- PubChem CID
- 5702160
Also known as
famotidine · Pepdul · Gastridin · Pepdine · Famodil · Gaster · Ganor · Gastropen
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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