API reference
Febuxostat
- CAS number
- 144060-53-7
- Molecular formula
- C16H16N2O3S
- Molecular weight
- 316.4 g/mol
About this molecule
Febuxostat is an orally available, non-purine inhibitor of xanthine oxidase with uric acid lowering activity. Upon oral administration, febuxostat selectively and noncompetitively inhibits the activity of xanthine oxidase, an enzyme that converts oxypurines, including hypoxanthine and xanthine, into uric acid. By inhibiting xanthine oxidase, uric acid production is reduced and serum uric acid levels are lowered. Febuxostat may provide protection against acute renal failure caused by the excessive release of uric acid that occurs upon massive tumor cell lysis resulting from the treatment of some malignancies.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid
- InChIKey
- BQSJTQLCZDPROO-UHFFFAOYSA-N
- SMILES
- CC1=C(SC(=N1)C2=CC(=C(C=C2)OCC(C)C)C#N)C(=O)O
- PubChem CID
- 134018
Also known as
Febuxostat · Adenuric · Uloric · TMX-67 · TMX 67 · Zurig · Febuxostatum · Febuxostat tablets 40 mg
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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