API reference
Finerenone
- CAS number
- 1050477-31-0
- Molecular formula
- C21H22N4O3
- Molecular weight
- 378.4 g/mol
About this molecule
Finerenone is an orally bioavailable non-steroidal mineralocorticoid receptor antagonist (MRA), with anti-fibrotic and anti-inflammatory activities. Upon oral administration, finerenone targets and binds to the mineralocorticoid receptor (MR), and inhibits MR-mediated sodium reabsorption and overactivation in both epithelial and nonepithelial tissues. This reduces fibrosis and inflammation that result from MR overactivation.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- (4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide
- InChIKey
- BTBHLEZXCOBLCY-QGZVFWFLSA-N
- SMILES
- CCOC1=NC=C(C2=C1[C@@H](C(=C(N2)C)C(=O)N)C3=C(C=C(C=C3)C#N)OC)C
- PubChem CID
- 60150535
Also known as
Finerenone · Kerendia · finerenona · finerenonum · 814-499-5 · Finerenone (JAN/USAN/INN) · Finerenon · Finerenone?
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