API reference
Flucloxacillin
- CAS number
- 5250-39-5
- Molecular formula
- C19H17ClFN3O5S
- Molecular weight
- 453.9 g/mol
About this molecule
Flucloxacillin is a narrow-spectrum, semisynthetic isoxazolyl penicillin with antibacterial activity. Floxacillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- (2S,5R,6R)-6-[[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
- InChIKey
- UIOFUWFRIANQPC-JKIFEVAISA-N
- SMILES
- CC1=C(C(=NO1)C2=C(C=CC=C2Cl)F)C(=O)N[C@H]3[C@@H]4N(C3=O)[C@H](C(S4)(C)C)C(=O)O
- PubChem CID
- 21319
Also known as
Flucloxacillin · flucloxacilina · Flucloxacilline · Flucloxacillinum · Fluorochloroxacillin · 3-(2-Chloro-6-fluorophenyl)-5-methyl-4-isoxazolylpenicillin · flucloxacillina · ABBOFLOX
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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