API reference
Flumazenil
- CAS number
- 78755-81-4
- Molecular formula
- C15H14FN3O3
- Molecular weight
- 303.29 g/mol
About this molecule
Flumazenil is an imidazo-benzodiazepine derivative, effective in reversing benzodiazepine-induced activities. Flumazenil antagonizes the benzodiazepine binding site of the gamma-aminobutyric acid (GABA)/benzodiazepine receptor complex in the central nervous system (CNS), thereby preventing the chloride channel opening events and inhibiting neuronal hyperpolarization. As a result, flumazenil reverses benzodiazepine-induced effects including sedation, psychomotor deficits, amnesia, and hypoventilation in a dose-dependent manner.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- ethyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate
- InChIKey
- OFBIFZUFASYYRE-UHFFFAOYSA-N
- SMILES
- CCOC(=O)C1=C2CN(C(=O)C3=C(N2C=N1)C=CC(=C3)F)C
- PubChem CID
- 3373
Also known as
flumazenil · Anexate · Flumazepil · Romazicon · Lanexat · Mazicon · Flumazenilo · Flumazenilum
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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