API reference

Fluorometholone

CAS number
426-13-1
Molecular formula
C22H29FO4
Molecular weight
376.5 g/mol
Fluorometholone — 2D structure
2D structure (PubChem)

About this molecule

Fluorometholone is a member of the class of glucocorticoids that is 1-progesterone substituted at positions 11beta and 17 by hydroxy groups, at position 6alpha by a methyl group and at position 9 by a fluoro group. Used for the treatment of corticosteroid-responsive inflammation of the palpebral and bulbar conjunctiva, cornea and anterior segment of the globe. It has a role as an anti-inflammatory drug. It is a tertiary alpha-hydroxy ketone, a glucocorticoid, a 17alpha-hydroxy steroid, an 11beta-hydroxy steroid, a 20-oxo steroid, a fluorinated steroid and a 3-oxo-Delta(1),Delta(4)-steroid. It is functionally related to a Delta(1)-progesterone.

Source: ChEBI, via PubChem.

Identifiers

IUPAC name
(6S,8S,9R,10S,11S,13S,14S,17R)-17-acetyl-9-fluoro-11,17-dihydroxy-6,10,13-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
InChIKey
FAOZLTXFLGPHNG-KNAQIMQKSA-N
SMILES
C[C@H]1C[C@H]2[C@@H]3CC[C@@]([C@]3(C[C@@H]([C@@]2([C@@]4(C1=CC(=O)C=C4)C)F)O)C)(C(=O)C)O
PubChem CID
9878

Also known as

fluorometholone · Oxylone · Fluor-Op · FML Forte · Fluorometolona · Fluorometholonum · Fluorometolone · Fluaton

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