API reference

Flurandrenolide

CAS number
1524-88-5
Molecular formula
C24H33FO6
Molecular weight
436.5 g/mol
Flurandrenolide — 2D structure
2D structure (PubChem)

About this molecule

Flurandrenolide is a synthetic glucocorticoid with anti-inflammatory and anti-allergic properties. Flurandrenolide exerts its effects by interacting with specific cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor mediated gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions.

Source: NCI Thesaurus (NCIt), via PubChem.

Identifiers

IUPAC name
(1S,2S,4R,8S,9S,11S,12S,13R,19S)-19-fluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icos-17-en-16-one
InChIKey
POPFMWWJOGLOIF-XWCQMRHXSA-N
SMILES
C[C@]12CCC(=O)C=C1[C@H](C[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3C[C@@H]5[C@]4(OC(O5)(C)C)C(=O)CO)C)O)F
PubChem CID
15209

Also known as

flurandrenolide · Fludroxycortide · Flurandrenolone · Cordran · Haelan · Fluorandrenolone · Drenison · Drocort

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