API reference
Flurbiprofen
- CAS number
- 5104-49-4
- Molecular formula
- C15H13FO2
- Molecular weight
- 244.26 g/mol
About this molecule
Flurbiprofen is a derivative of propionic acid, and a phenylalkanoic acid derivative of non-steroidal antiinflammatory drugs (NSAIDs) with analgesic, antiinflammatory and antipyretic effects. Flurbiprofen non-selectively binds to and inhibits cyclooxygenase (COX). This results in a reduction of arachidonic acid conversion into prostaglandins that are involved in the regulation of pain, inflammation and fever. This NSAID also inhibits carbonic anhydrase, thereby reducing the production of hydrogen and bicarbonate ions. Upon ocular administration, flurbiprofen may reduce bicarbonate ion concentrations leading to a decrease in the production of aqueous humor, thereby lowering intraocular pressure.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 2-(3-fluoro-4-phenylphenyl)propanoic acid
- InChIKey
- SYTBZMRGLBWNTM-UHFFFAOYSA-N
- SMILES
- CC(C1=CC(=C(C=C1)C2=CC=CC=C2)F)C(=O)O
- Other CAS numbers recorded
- 51543-38-5
- PubChem CID
- 3394
Also known as
flurbiprofen · Ansaid · Froben · Antadys · 2-(3-fluoro-4-phenylphenyl)propanoic acid · Cebutid · Zepolas · Flurbiprofene
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