API reference
Fosamprenavir calcium
- CAS number
- 226700-81-8
- Molecular formula
- C25H34CaN3O9PS
- Molecular weight
- 623.7 g/mol
About this molecule
Fosamprenavir Calcium is the calcium salt form of fosamprenavir, prodrug of amprenavir, and a human immunodeficiency virus (HIV) protease inhibitor with antiviral property. Fosamprenavir is converted to amprenavir by cellular phosphatases in the epithelial cells of the intestine. Then amprenavir binds to the active site of HIV-1 protease, thereby preventing the proteolytic cleavage of viral Gag-Pol polypeptide into individual functional proteins, thereby leading to the formation of immature non-infectious viral particles.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- calcium [(2R,3S)-1-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-[[(3S)-oxolan-3-yl]oxycarbonylamino]-4-phenylbutan-2-yl] phosphate
- InChIKey
- PMDQGYMGQKTCSX-HQROKSDRSA-L
- SMILES
- CC(C)CN(C[C@H]([C@H](CC1=CC=CC=C1)NC(=O)O[C@H]2CCOC2)OP(=O)([O-])[O-])S(=O)(=O)C3=CC=C(C=C3)N.[Ca+2]
- PubChem CID
- 131535
Also known as
Fosamprenavir calcium · Fosamprenavir Calcium Salt · Lexiva · Telzir · Fosamprenavir (Calcium Salt) · Fosamprenavir calcium (USAN) · Amprenavir phosphate calcium · Lexiva (TN)
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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