API reference
Foscarnet sodium
- CAS number
- 63585-09-1
- Molecular formula
- CNa3O5P
- Molecular weight
- 191.95 g/mol
About this molecule
Foscarnet Sodium is the trisodium salt of a synthetic organic analogue of inorganic pyrophosphate with antiviral activity. Foscarnet selectively blocks the pyrophosphate binding site of herpesvirus-specific DNA polymerases at concentrations that do not affect cellular DNA polymerases. This agent does not require phosphorylation by thymidine kinase (TK) or other kinases and therefore is active in vitro against herpes simplex virus (HSV) TK deficient mutants and cytomegalovirus (CMV) UL97 mutants. Because foscarnet crosses the blood brain barrier, it may be used in the treatment of viral infections of the CNS.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- trisodium;phosphonatoformate
- InChIKey
- DFHAXXVZCFXGOQ-UHFFFAOYSA-K
- SMILES
- C(=O)([O-])P(=O)([O-])[O-].[Na+].[Na+].[Na+]
- PubChem CID
- 44561
Also known as
FOSCARNET SODIUM · Foscavir · Foscarnet sodico · EHB 776 · Phosphonoformic acid, trisodium salt · Phosphinecarboxylic acid, dihydroxy-, oxide, trisodium salt · EHB-776 · Foscarnet sodium anhydrous
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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