API reference
Fosfomycin tromethamine
- CAS number
- 78964-85-9
- Molecular formula
- C7H18NO7P
- Molecular weight
- 259.19 g/mol
About this molecule
Fosfomycin Tromethamine is the tromethamine salt form of fosfomycin, a synthetic broad-spectrum antibiotic. Fosfomycin tromethamine binds to and inactivates the enzyme enolpyruvyl transferase. This leads to an irreversible blockage of the condensation of uridine diphosphate-N-acetylglucosamine with p-enolpyruvate, which is one of the first steps of bacterial cell wall synthesis, thereby eventually causing cell lysis. In addition, fosfomycin tromethamine reduces the adherence of bacteria to uroepithelial cells. (NCI05)
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 2-amino-2-(hydroxymethyl)propane-1,3-diol;[(2R,3S)-3-methyloxiran-2-yl]phosphonic acid
- InChIKey
- QZJIMDIBFFHQDW-LMLSDSMGSA-N
- SMILES
- C[C@H]1[C@H](O1)P(=O)(O)O.C(C(CO)(CO)N)O
- PubChem CID
- 10199068
Also known as
FOSFOMYCIN TROMETHAMINE · Fosfomycin trometamol · Fosfomycin trometamol (1:1) · Fosfomycin trometamol salt · Granules for Oral · Granules for Oral Solution · Fosfomycin compound with Trometamol · 279-018-8
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