API reference
Fosphenytoin sodium
- CAS number
- 92134-98-0
- Molecular formula
- C16H13N2Na2O6P
- Molecular weight
- 406.24 g/mol
About this molecule
Fosphenytoin Sodium is the sodium salt form of fosphenytoin, a prodrug that is hydrolyzed to the anticonvulsant phenytoin upon parental administration. Phenytoin exerts its effect most likely through an enhancement of sodium efflux from neurons in the motor cortex. This leads to a suppression of excessive neuronal firing and spread of seizure activity. Other physiologic effects from actions of phenytoin include modulation of the voltage-dependent calcium channels of neurons, inhibition of calcium flux across neuronal membranes and enhancement of sodium-potassium ATPase activity of neurons and glial cells. (NCI05)
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- disodium;(2,5-dioxo-4,4-diphenylimidazolidin-1-yl)methyl phosphate
- InChIKey
- GQPXYJNXTAFDLT-UHFFFAOYSA-L
- SMILES
- C1=CC=C(C=C1)C2(C(=O)N(C(=O)N2)COP(=O)([O-])[O-])C3=CC=CC=C3.[Na+].[Na+]
- PubChem CID
- 56338
Also known as
Fosphenytoin sodium · Fosphenytoin disodium salt · Pro-Epanutin · CI 982 · CI-982 · Sesquient · Fosphenytoin disodium · Cerebyx
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