API reference
Fulvestrant
- CAS number
- 129453-61-8
- Molecular formula
- C32H47F5O3S
- Molecular weight
- 606.8 g/mol
About this molecule
Fulvestrant is a drug treatment of hormone receptor (HR)-positive metastatic breast cancer in post-menopausal women with disease progression following anti-estrogen therapy. It is an estrogen receptor antagonist with no agonist effects, which works both by down-regulating and by degrading the estrogen receptor. While it is used as monotherapy for the treatment of breast cancers, it is also used in combination with [alpelisib] for the treatment of HR-positive, human epidermal growth factor receptor 2 (HER2)-negative, PIK3CA-mutated, advanced or metastatic breast cancer
Source: DrugBank, via PubChem.
Identifiers
- IUPAC name
- (7R,8R,9S,13S,14S,17S)-13-methyl-7-[9-(4,4,5,5,5-pentafluoropentylsulfinyl)nonyl]-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol
- InChIKey
- VWUXBMIQPBEWFH-WCCTWKNTSA-N
- SMILES
- C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)[C@@H](CC4=C3C=CC(=C4)O)CCCCCCCCCS(=O)CCCC(C(F)(F)F)(F)F
- Other CAS numbers recorded
- 1316849-17-8
- PubChem CID
- 104741
Also known as
Fulvestrant · Faslodex · ICI 182,780 · fulvestrantum · Faslodex(ICI 182,780) · L02BA03 · 642-998-6 · Fulvestrant (Standard)
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
Tell us the grade, the quantity and the market.
Send the molecule or ingredient, the specification and the destination. We reply from Tehran with the questions, the documents and the next step.