API reference

Gadoterate meglumine

CAS number
92943-93-6
Molecular formula
C23H42GdN5O13
Molecular weight
753.9 g/mol
Gadoterate meglumine — 2D structure
2D structure (PubChem)

About this molecule

Gadoterate Meglumine is a gadolinium chelate paramagnetic contrast agent. When placed in a magnetic field, gadoterate meglumine produces a large magnetic moment and so a large local magnetic field, which can enhance the relaxation rate of nearby protons; as a result, the signal intensity of tissue images observed with magnetic resonance imaging (MRI) may be enhanced. Because this agent is preferentially taken up by normal functioning hepatocytes, normal hepatic tissue is enhanced with MRI while tumor tissue is unenhanced. In addition, because gadobenate dimeglumine is excreted in the bile, it may be used to visualize the biliary system using MRI.

Source: NCI Thesaurus (NCIt), via PubChem.

Identifiers

IUPAC name
2-[4,7-bis(carboxylatomethyl)-10-(carboxymethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetate;gadolinium(3+);(2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol
InChIKey
RYHQMKVRYNEBNJ-BMWGJIJESA-K
SMILES
CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O.C1CN(CCN(CCN(CCN1CC(=O)O)CC(=O)[O-])CC(=O)[O-])CC(=O)[O-].[Gd+3]
PubChem CID
6918037

Also known as

Dotarem · Magnescope · P449 · P-449 · CLARISCAN · Gadolinium-dota meglumine · Gadoterate Meglumine · Gd-dota meglumine

Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.

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