API reference
Galantamine hydrobromide
- CAS number
- 1953-04-4
- Molecular formula
- C17H22BrNO3
- Molecular weight
- 368.3 g/mol
About this molecule
Galantamine Hydrobromide is the hydrobromide salt form of galantamine, a tertiary alkaloid obtained synthetically or naturally from the bulbs and flowers of Narcissus and several other genera of the Amaryllidaceae family with anticholinesterase and neurocognitive-enhancing activities. Galantamine competitively and reversibly inhibits acetylcholinesterase, thereby increasing the concentration and enhancing the action of acetylcholine (Ach). In addition, galantamine is a ligand for nicotinic acetylcholine receptors, which may increase the presynaptic release of Ach and activate postsynaptic receptors. This agent may improve neurocognitive function in mild and moderate Alzheimer' s disease and may reduce abstinence-induced cognitive symptoms that promote smoking relapse.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- (1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraen-14-ol;hydrobromide
- InChIKey
- QORVDGQLPPAFRS-XPSHAMGMSA-N
- SMILES
- CN1CC[C@@]23C=C[C@@H](C[C@@H]2OC4=C(C=CC(=C34)C1)OC)O.Br
- Other CAS numbers recorded
- 193146-85-9
- PubChem CID
- 121587
Also known as
Galanthamine hydrobromide · Galantamine hydrobromide · Nivaline · Nivalin · Lycoremine hydrobromide · Jilkon hydrobromide · Tamilin · Razadyne ER
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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