API reference
Ganciclovir sodium
- CAS number
- 107910-75-8
- Molecular formula
- C9H12N5NaO4
- Molecular weight
- 277.21 g/mol
About this molecule
Ganciclovir Sodium is the sodium salt form of ganciclovir, a synthetic, antiviral, purine nucleoside analog with antiviral activity, especially against cytomegalovirus (CMV). Ganciclovir sodium is a prodrug that is phosphorylated and subsequently converted into its triphosphate form, the active metabolite ganciclovir-5-triphosphate (ganciclovir-TP), in the infected cells by cellular kinases. Ganciclovir-TP competes as a substrate with nucleotide triphosphates for viral DNA polymerase. Once it gets incorporated into DNA strand, it prevents further polymerization of DNA, thereby interfering with viral DNA replication.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- sodium 2-amino-9-(1,3-dihydroxypropan-2-yloxymethyl)purin-6-olate
- InChIKey
- JJICLMJFIKGAAU-UHFFFAOYSA-M
- SMILES
- C1=NC2=C(N1COC(CO)CO)N=C(N=C2[O-])N.[Na+]
- Other CAS numbers recorded
- 84245-13-6
- PubChem CID
- 23700083
Also known as
GANCICLOVIR SODIUM · Ganciclovir Sodium Salt · Cytovene IV · Cytovene-IV · Ganciclovir (as sodium) · DHPG Sodium · GCV Sodium · denosine
Related entries in the range
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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