API reference
Glyburide
- CAS number
- 10238-21-8
- Molecular formula
- C23H28ClN3O5S
- Molecular weight
- 494 g/mol
About this molecule
Glyburide is a second generation sulfonylurea used to treat patients with diabetes mellitus type II. It is typically given to patients who cannot be managed with the standard first line therapy, [metformin]. Glyburide stimulates insulin secretion through the closure of ATP-sensitive potassium channels on beta cells, raising intracellular potassium and calcium ion concentrations. Glyburide was granted FDA approval on 1 May 1984. A formulation with metformin was granted FDA approval on on 31 July 2000.
Source: DrugBank, via PubChem.
Identifiers
- IUPAC name
- 5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide
- InChIKey
- ZNNLBTZKUZBEKO-UHFFFAOYSA-N
- SMILES
- COC1=C(C=C(C=C1)Cl)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3
- PubChem CID
- 3488
Also known as
Glibenclamide · glyburide · Glynase · Euglucon · Semi-daonil · Libanil · Lederglib · Calabren
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
Tell us the grade, the quantity and the market.
Send the molecule or ingredient, the specification and the destination. We reply from Tehran with the questions, the documents and the next step.