API reference
Granisetron
- CAS number
- 109889-09-0
- Molecular formula
- C18H24N4O
- Molecular weight
- 312.4 g/mol
About this molecule
Granisetron is a monocarboxylic acid amide resulting from the formal condensation of the carboxy group of 1-methyl-1H-indazole-3-carboxylic acid with the primary amino group of (3-endo)-9-methyl-9-azabicyclo[3.3.1]nonan-3-amine. A selective 5-HT3 receptor antagonist, it is used (generally as the monohydrochloride salt) to manage nausea and vomiting caused by cancer chemotherapy and radiotherapy, and to prevent and treat postoperative nausea and vomiting. It has a role as a serotonergic antagonist and an antiemetic. It is a monocarboxylic acid amide, a member of indazoles and a tertiary amino compound.
Source: ChEBI, via PubChem.
Identifiers
- IUPAC name
- 1-methyl-N-[(1R,5S)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]indazole-3-carboxamide
- InChIKey
- MFWNKCLOYSRHCJ-AGUYFDCRSA-N
- SMILES
- CN1[C@@H]2CCC[C@H]1CC(C2)NC(=O)C3=NN(C4=CC=CC=C43)C
- Other CAS numbers recorded
- 1364914-39-5
- PubChem CID
- 5284566
Also known as
Granisetron (JAN/USAN/INN) · granisetron · Sancuso · Sustol · exo-Granisetron · Kevatril · Granisetronum · APF530
Related entries in the range
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