API reference
Griseofulvin
- CAS number
- 126-07-8
- Molecular formula
- C17H17ClO6
- Molecular weight
- 352.8 g/mol
About this molecule
Griseofulvin is only found in individuals that have used or taken this drug. It is an antifungal antibiotic. Griseofulvin may be given by mouth in the treatment of tinea infections. Griseofulvin is fungistatic, however the exact mechanism by which it inhibits the growth of dermatophytes is not clear. It is thought to inhibit fungal cell mitosis and nuclear acid synthesis. It also binds to and interferes with the function of spindle and cytoplasmic microtubules by binding to alpha and beta tubulin. It binds to keratin in human cells, then once it reaches the fungal site of action, it binds to fungal microtubes thus altering the fungal process of mitosis.
Source: Toxin and Toxin Target Database (T3DB), via PubChem.
Identifiers
- IUPAC name
- (2S,5'R)-7-chloro-3',4,6-trimethoxy-5'-methylspiro[1-benzofuran-2,4'-cyclohex-2-ene]-1',3-dione
- InChIKey
- DDUHZTYCFQRHIY-RBHXEPJQSA-N
- SMILES
- C[C@@H]1CC(=O)C=C([C@]12C(=O)C3=C(O2)C(=C(C=C3OC)OC)Cl)OC
- Other CAS numbers recorded
- 2884-22-2 · 107912-37-8
- PubChem CID
- 441140
Also known as
griseofulvin · (+)-Griseofulvin · Fulvicin · Amudane · Fulcin · Griseofulvina · Griseofulvinum · Spirofulvin
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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