API reference
Guaifenesin
- CAS number
- 93-14-1
- Molecular formula
- C10H14O4
- Molecular weight
- 198.22 g/mol

About this molecule
Guaifenesin is a glyceryl guaiacolate with expectorant effects. Guaifenesin increases respiratory tract mucus secretions, acts as an irritant to gastric vagal receptors and recruits efferent parasympathetic reflexes that cause glandular exocytosis. This agent reduces the viscosity of mucus secretion by reducing adhesiveness and surface tension as well as increasing hydration of mucus. Guaifenesin promotes the efficiency of the mucociliary mechanism important in removing accumulated secretions from the upper and lower airway.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 3-(2-methoxyphenoxy)propane-1,2-diol
- InChIKey
- HSRJKNPTNIJEKV-UHFFFAOYSA-N
- SMILES
- COC1=CC=CC=C1OCC(CO)O
- PubChem CID
- 3516
Also known as
guaifenesin · Guaiphenesin · Guaiacol glyceryl ether · 3-(2-methoxyphenoxy)propane-1,2-diol · Glycerol guaiacolate · GLYCERYL GUAIACOLATE · Methphenoxydiol · Guaiphenesine
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