API reference

Guaifenesin

CAS number
93-14-1
Molecular formula
C10H14O4
Molecular weight
198.22 g/mol
Guaifenesin — 2D structure
2D structure (PubChem)

About this molecule

Guaifenesin is a glyceryl guaiacolate with expectorant effects. Guaifenesin increases respiratory tract mucus secretions, acts as an irritant to gastric vagal receptors and recruits efferent parasympathetic reflexes that cause glandular exocytosis. This agent reduces the viscosity of mucus secretion by reducing adhesiveness and surface tension as well as increasing hydration of mucus. Guaifenesin promotes the efficiency of the mucociliary mechanism important in removing accumulated secretions from the upper and lower airway.

Source: NCI Thesaurus (NCIt), via PubChem.

Identifiers

IUPAC name
3-(2-methoxyphenoxy)propane-1,2-diol
InChIKey
HSRJKNPTNIJEKV-UHFFFAOYSA-N
SMILES
COC1=CC=CC=C1OCC(CO)O
PubChem CID
3516

Also known as

guaifenesin · Guaiphenesin · Guaiacol glyceryl ether · 3-(2-methoxyphenoxy)propane-1,2-diol · Glycerol guaiacolate · GLYCERYL GUAIACOLATE · Methphenoxydiol · Guaiphenesine

Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.

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