API reference
Halcinonide
- CAS number
- 3093-35-4
- Molecular formula
- C24H32ClFO5
- Molecular weight
- 455 g/mol
About this molecule
Halcinonide is a topical, synthetic glucocorticoid with anti-inflammatory and anti-allergic properties. Halcinonide exerts its effect by interacting with specific intracellular receptors, and the ligand-receptor complex subsequently modulates gene expressions via the typical glucocorticoid signalling pathway. This results in the synthesis of certain anti-inflammatory proteins as well as in synthesis inhibition of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions are accomplished. (NCI05)
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- (1S,2S,4R,8S,9S,11S,12R,13S)-8-(2-chloroacetyl)-12-fluoro-11-hydroxy-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icos-17-en-16-one
- InChIKey
- MUQNGPZZQDCDFT-JNQJZLCISA-N
- SMILES
- C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@]2([C@H](C[C@]4([C@H]3C[C@@H]5[C@]4(OC(O5)(C)C)C(=O)CCl)C)O)F
- PubChem CID
- 443943
Also known as
halcinonide · Halciderm · Halcimat · Halog · Alcinonide · Halcinonida · Halcort · Halcinonidum
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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