API reference
Haloperidol
- CAS number
- 52-86-8
- Molecular formula
- C21H23ClFNO2
- Molecular weight
- 375.9 g/mol
About this molecule
Haloperidol is a phenylbutylpiperadine derivative with antipsychotic, neuroleptic, and antiemetic activities. Haloperidol competitively blocks postsynaptic dopamine (D2) receptors in the mesolimbic system of the brain, thereby eliminating dopamine neurotransmission and leading to antidelusionary and antihallucinagenic effects. Antagonistic activity mediated through D2 dopamine receptors in the chemoreceptive trigger zone (CTZ) accounts for its antiemetic activity.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one
- InChIKey
- LNEPOXFFQSENCJ-UHFFFAOYSA-N
- SMILES
- C1CN(CCC1(C2=CC=C(C=C2)Cl)O)CCCC(=O)C3=CC=C(C=C3)F
- Other CAS numbers recorded
- 177716-59-5
- PubChem CID
- 3559
Also known as
haloperidol · Serenace · Aloperidin · Serenelfi · Eukystol · Linton · Serenase · Aloperidolo
Related entries in the range
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