API reference
Homoharringtonine
- CAS number
- 26833-87-4
- Molecular formula
- C29H39NO9
- Molecular weight
- 545.6 g/mol

About this molecule
Omacetaxine mepesuccinate is a cephalotaxine-derived alkaloid ester obtained from Cephalotaxus harringtonia; used for the treatment of chronic or accelerated phase chronic myeloid leukaemia. It has a role as an anticoronaviral agent, an antineoplastic agent, a protein synthesis inhibitor and an apoptosis inducer. It is a tertiary alcohol, an organic heteropentacyclic compound, an alkaloid ester and an enol ether. It is functionally related to a cephalotaxine.
Source: ChEBI, via PubChem.
Identifiers
- IUPAC name
- 1-O-[(2S,3S,6R)-4-methoxy-16,18-dioxa-10-azapentacyclo[11.7.0.02,6.06,10.015,19]icosa-1(20),4,13,15(19)-tetraen-3-yl] 4-O-methyl (2R)-2-hydroxy-2-(4-hydroxy-4-methylpentyl)butanedioate
- InChIKey
- HYFHYPWGAURHIV-JFIAXGOJSA-N
- SMILES
- CC(C)(CCC[C@@](CC(=O)OC)(C(=O)O[C@H]1[C@H]2C3=CC4=C(C=C3CCN5[C@@]2(CCC5)C=C1OC)OCO4)O)O
- PubChem CID
- 285033
Also known as
Omacetaxine mepesuccinate · Ceflatonin · Myelostat · Synribo · CGX-635 · Omapro · Homoharringtonin · (-)-homoharringtonine
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