API reference
HYDRALAZINE HCl
- CAS number
- 304-20-1
- Molecular formula
- C8H9ClN4
- Molecular weight
- 196.64 g/mol
About this molecule
Hydralazine Hydrochloride is the hydrochloride salt of hydralazine, a phthalazine derivative with antihypertensive and potential antineoplastic activities. Hydralazine alters intracellular calcium release and interferes with smooth muscle cell calcium influx, resulting in arterial vasodilatation. This agent also inhibits the phosphorylation of myosin protein and chelation of trace metals required for smooth muscle contraction, resulting in an increase in heart rate, stroke volume and cardiac output. In addition to its cardiovascular effects, hydralazine inhibits DNA methyltransferase, which may result in inhibition of DNA methylation in tumor cells.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- phthalazin-1-ylhydrazine;hydrochloride
- InChIKey
- ZUXNZUWOTSUBMN-UHFFFAOYSA-N
- SMILES
- C1=CC=C2C(=C1)C=NN=C2NN.Cl
- Other CAS numbers recorded
- 1542530-01-7
- PubChem CID
- 9351
Also known as
HYDRALAZINE HYDROCHLORIDE · HYDRALAZINE HCL · 1-Hydrazinophthalazine hydrochloride · Dralzine · Hydralazine chloride · Hydralazine monohydrochloride · 1-Hydrazinophthalazine monohydrochloride · Apressinum
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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