API reference

Hydrocortisone

CAS number
50-23-7
Molecular formula
C21H30O5
Molecular weight
362.5 g/mol
Hydrocortisone — 2D structure
2D structure (PubChem)

About this molecule

Therapeutic Hydrocortisone is a synthetic or semisynthetic analog of natural hydrocortisone hormone produced by the adrenal glands with primary glucocorticoid and minor mineralocorticoid effects. As a glucocorticoid receptor agonist, hydrocortisone promotes protein catabolism, gluconeogenesis, capillary wall stability, renal excretion of calcium, and suppresses immune and inflammatory responses. (NCI04)

Source: NCI Thesaurus (NCIt), via PubChem.

Identifiers

IUPAC name
(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
InChIKey
JYGXADMDTFJGBT-VWUMJDOOSA-N
SMILES
C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@]4(C(=O)CO)O)C)O
PubChem CID
5754

Also known as

hydrocortisone · Cortisol · Acticort · Cetacort · Hydrocortisyl · Cobadex · Hytone · Cortenema

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