API reference

HYDROXYZINE HCl

CAS number
2192-20-3
Molecular formula
C21H29Cl3N2O2
Molecular weight
447.8 g/mol
HYDROXYZINE HCl — 2D structure
2D structure (PubChem)

About this molecule

Hydroxyzine Hydrochloride is the hydrochloride salt form of hydroxyzine, a piperazine histamine H1-receptor antagonist with anti-allergic, antispasmodic, sedative, anti-emetic and anti-anxiety properties. Hydroxyzine hydrochloride blocks the H1 histamine receptor and prevents the symptoms that are caused by histamine activity on capillaries, bronchial smooth muscle, and gastrointestinal smooth muscle, including vasodilatation, increased capillary permeability, bronchoconstriction, and spasmodic contraction of gastrointestinal smooth muscle. In addition, hydroxyzine hydrochloride crosses the blood-brain barrier and acts on the histamine H1-receptors in the central nervous system. (NCI05)

Source: NCI Thesaurus (NCIt), via PubChem.

Identifiers

IUPAC name
2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]ethanol;dihydrochloride
InChIKey
ANOMHKZSQFYSBR-UHFFFAOYSA-N
SMILES
C1CN(CCN1CCOCCO)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl.Cl
Other CAS numbers recorded
163837-38-5 · 163837-37-4
PubChem CID
91513

Also known as

Hydroxyzine dihydrochloride · Hydroxyzine hydrochloride · Orgatrax · Atranine A · Hydroxyzine Hcl · Atarax dihydrochloride · Anxanil · Ucerax

Related entries in the range

Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.

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