API reference
HYDROXYZINE HCl
- CAS number
- 2192-20-3
- Molecular formula
- C21H29Cl3N2O2
- Molecular weight
- 447.8 g/mol

About this molecule
Hydroxyzine Hydrochloride is the hydrochloride salt form of hydroxyzine, a piperazine histamine H1-receptor antagonist with anti-allergic, antispasmodic, sedative, anti-emetic and anti-anxiety properties. Hydroxyzine hydrochloride blocks the H1 histamine receptor and prevents the symptoms that are caused by histamine activity on capillaries, bronchial smooth muscle, and gastrointestinal smooth muscle, including vasodilatation, increased capillary permeability, bronchoconstriction, and spasmodic contraction of gastrointestinal smooth muscle. In addition, hydroxyzine hydrochloride crosses the blood-brain barrier and acts on the histamine H1-receptors in the central nervous system. (NCI05)
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]ethanol;dihydrochloride
- InChIKey
- ANOMHKZSQFYSBR-UHFFFAOYSA-N
- SMILES
- C1CN(CCN1CCOCCO)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl.Cl
- Other CAS numbers recorded
- 163837-38-5 · 163837-37-4
- PubChem CID
- 91513
Also known as
Hydroxyzine dihydrochloride · Hydroxyzine hydrochloride · Orgatrax · Atranine A · Hydroxyzine Hcl · Atarax dihydrochloride · Anxanil · Ucerax
Related entries in the range
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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