API reference
Ibuprofen
- CAS number
- 58560-75-1
- Molecular formula
- C13H18O2
- Molecular weight
- 206.28 g/mol
About this molecule
Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) widely marketed under various trademarks including Act-3, Advil, Brufen, Motrin, Nuprin, and Nurofen. It is used for relief of symptoms of arthritis, primary dysmenorrhoea, and fever; Ibuprofen is an NSAID which is believed to work through inhibition of cyclooxygenase (COX), thus inhibiting prostaglandin synthesis. There are at least 2 variations of cyclooxygenase (COX-1 and COX-2), ibuprofen inhibits both COX-1 and COX-2. It appears that its analgesic, antipyretic, and anti-inflammatory activity are achieved principally through COX-2 inhibition; whereas COX-1 inhibition is responsible for its unwanted effects on platelet aggregation and the GI mucosa. As with other NSAIDs, ibuprofen inhibits platelet aggregation, but is not used therapeutically for this action since it is a minor and reversible effect. -- Wikipedia.
Source: Toxin and Toxin Target Database (T3DB), via PubChem.
Identifiers
- IUPAC name
- 2-[4-(2-methylpropyl)phenyl]propanoic acid
- InChIKey
- HEFNNWSXXWATRW-UHFFFAOYSA-N
- SMILES
- CC(C)CC1=CC=C(C=C1)C(C)C(=O)O
- Other CAS numbers recorded
- 15687-27-1
- PubChem CID
- 3672
Also known as
IBUPROFEN, (+-)- · ibuprofen · 2-(4-Isobutylphenyl)propanoic acid · Brufen · Motrin · Advil · Liptan · Medipren
Related entries in the range
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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