API reference
Indomethacin sodium
- CAS number
- 7681-54-1
- Molecular formula
- C19H15ClNNaO4
- Molecular weight
- 379.8 g/mol

About this molecule
Indomethacin Sodium is the sodium salt of indomethacin, a methylated indole derivative with anti-inflammatory, analgesic-antipyretic and tocolytic effects. Indomethacin is a non-selective, reversible, and competitive inhibitor of cyclooxygenases 1 and 2, thereby blocking the conversion of arachidonic acid into prostaglandin precursors. Consequently, prostaglandin synthesis is decreased, and prostaglandin-mediated activities are prevented, including pain, inflammation, fever and uterine contraction.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- sodium 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetate
- InChIKey
- JMHRGKDWGWORNU-UHFFFAOYSA-M
- SMILES
- CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)[O-].[Na+]
- Other CAS numbers recorded
- 74252-25-8
- PubChem CID
- 23675763
Also known as
INDOMETHACIN SODIUM · Sodium indomethacin · Indometacin sodium · Indocin I.V. · Indomethacin sodium anhydrous · INDOMETACIN SODIUM (MART.) · INDOMETHACIN SODIUM (USP MONOGRAPH) · 231-670-4
Related entries in the range
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