API reference

Indomethacin sodium

CAS number
7681-54-1
Molecular formula
C19H15ClNNaO4
Molecular weight
379.8 g/mol
Indomethacin sodium — 2D structure
2D structure (PubChem)

About this molecule

Indomethacin Sodium is the sodium salt of indomethacin, a methylated indole derivative with anti-inflammatory, analgesic-antipyretic and tocolytic effects. Indomethacin is a non-selective, reversible, and competitive inhibitor of cyclooxygenases 1 and 2, thereby blocking the conversion of arachidonic acid into prostaglandin precursors. Consequently, prostaglandin synthesis is decreased, and prostaglandin-mediated activities are prevented, including pain, inflammation, fever and uterine contraction.

Source: NCI Thesaurus (NCIt), via PubChem.

Identifiers

IUPAC name
sodium 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetate
InChIKey
JMHRGKDWGWORNU-UHFFFAOYSA-M
SMILES
CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)[O-].[Na+]
Other CAS numbers recorded
74252-25-8
PubChem CID
23675763

Also known as

INDOMETHACIN SODIUM · Sodium indomethacin · Indometacin sodium · Indocin I.V. · Indomethacin sodium anhydrous · INDOMETACIN SODIUM (MART.) · INDOMETHACIN SODIUM (USP MONOGRAPH) · 231-670-4

Related entries in the range

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