API reference
Irbesartan
- CAS number
- 138402-11-6
- Molecular formula
- C25H28N6O
- Molecular weight
- 428.5 g/mol
About this molecule
Irbesartan is a nonpeptide angiotensin II antagonist with antihypertensive activity. Irbesartan selectively and competitively blocks the binding of angiotensin II to the angiotensin I receptor. Angiotensin II stimulates aldosterone synthesis and secretion by adrenal cortex, which decreases the excretion of sodium and increases the excretion of potassium. Angiotensin II also acts as a vasoconstrictor in vascular smooth muscle. (NCI05)
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 2-butyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one
- InChIKey
- YOSHYTLCDANDAN-UHFFFAOYSA-N
- SMILES
- CCCCC1=NC2(CCCC2)C(=O)N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5
- PubChem CID
- 3749
Also known as
irbesartan · Avapro · Aprovel · Karvea · Irbesartan BMS · Irbesartan Zentiva · Sarbevel · Irbesartan teva
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