API reference
Isoniazid
- CAS number
- 54-85-3
- Molecular formula
- C6H7N3O
- Molecular weight
- 137.14 g/mol
About this molecule
Isoniazid is a synthetic derivative of nicotinic acid with anti-mycobacterial properties. Although its mechanism of action is still unclear, isoniazid appears to block the synthesis of mycolic acids, major components of the mycobacterial cell wall. This agent is only active against actively growing mycobacteria because, as a pro-drug, it requires activation in susceptible mycobacterial species. Isoniazid also interferes with mycobacterial metabolism of vitamin B6. Resistance occurs due to decreased bacterial wall penetration. (NCI04)
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- pyridine-4-carbohydrazide
- InChIKey
- QRXWMOHMRWLFEY-UHFFFAOYSA-N
- SMILES
- C1=CN=CC=C1C(=O)NN
- PubChem CID
- 3767
Also known as
isoniazid · Isonicotinic acid hydrazide · Isonicotinohydrazide · pyridine-4-carbohydrazide · Isoniazide · Rimifon · Nydrazid · Cotinazin
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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