API reference
Ivacaftor
- CAS number
- 873054-44-5
- Molecular formula
- C24H28N2O3
- Molecular weight
- 392.5 g/mol
About this molecule
Ivacaftor is an aromatic amide obtained by formal condensation of the carboxy group of 4-oxo-1,4-dihydroquinoline-3-carboxylic acid with the amino group of 5-amino-2,4-di-tert-butylphenol. Used for the treatment of cystic fibrosis. It has a role as a CFTR potentiator and an orphan drug. It is a quinolone, a monocarboxylic acid amide, a member of phenols and an aromatic amide.
Source: ChEBI, via PubChem.
Identifiers
- IUPAC name
- N-(2,4-ditert-butyl-5-hydroxyphenyl)-4-oxo-1H-quinoline-3-carboxamide
- InChIKey
- PURKAOJPTOLRMP-UHFFFAOYSA-N
- SMILES
- CC(C)(C)C1=CC(=C(C=C1NC(=O)C2=CNC3=CC=CC=C3C2=O)O)C(C)(C)C
- Other CAS numbers recorded
- 1413431-05-6 · 1134822-00-6
- PubChem CID
- 16220172
Also known as
Ivacaftor · VX-770 · Kalydeco · ivacaftorum · ORKAMBI COMPONENT IVACAFTOR · SYMKEVI COMPONENT IVACAFTOR · TRIKAFTA COMPONENT IVACAFTOR · R07AX02
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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