API reference

Ketotifen hydrogen fumarate

CAS number
34580-14-8
Molecular formula
C23H23NO5S
Molecular weight
425.5 g/mol
Ketotifen hydrogen fumarate — 2D structure
2D structure (PubChem)

About this molecule

Ketotifen Fumarate is the fumarate salt of ketotifen, a cycloheptathiophene derivative with anti-allergic activity. Ketotifen selectively blocks histamine (H1) receptors and prevents the typical symptoms caused by histamine release. This agent also interferes with the release of inflammatory mediators from mast cells involved in hypersensitivity reactions, thereby decreasing chemotaxis and activation of eosinophils.

Source: NCI Thesaurus (NCIt), via PubChem.

Identifiers

IUPAC name
(E)-but-2-enedioic acid;2-(1-methylpiperidin-4-ylidene)-6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,10,12-pentaen-8-one
InChIKey
YNQQEYBLVYAWNX-WLHGVMLRSA-N
SMILES
CN1CCC(=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CC1.C(=C/C(=O)O)\C(=O)O
PubChem CID
5282408

Also known as

KETOTIFEN FUMARATE · Zaditen · Ketotifen hydrogen fumarate · Zaditor · Alaway · HC 20,511 fumarate · Ketotifen (as fumarate) · Itchy Eye

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