API reference
LABETALOL HCl
- CAS number
- 32780-64-6
- Molecular formula
- C19H25ClN2O3
- Molecular weight
- 364.9 g/mol
About this molecule
Labetalol Hydrochloride is the hydrochloride form of labetalol, a third generation selective alpha-1-adrenergic antagonist and non-selective beta-adrenergic antagonist with vasodilatory and antihypertensive properties. Labetalol competitively binds to alpha-1-adrenergic receptors in vascular smooth muscle, thereby inhibiting the adrenergic stimulation of endothelial cell function and vasoconstriction in peripheral blood vessels. This agent also binds to beta-receptors in the bronchial and vascular smooth muscle, resulting in a decrease in adrenergic stimulation. The result is a decrease in resting and exercise heart rates, cardiac output, and in both systolic and diastolic blood pressure, thereby resulting in vasodilation, and negative chronotropic and inotropic cardiac effects.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 2-hydroxy-5-[1-hydroxy-2-(4-phenylbutan-2-ylamino)ethyl]benzamide;hydrochloride
- InChIKey
- WQVZLXWQESQGIF-UHFFFAOYSA-N
- SMILES
- CC(CCC1=CC=CC=C1)NCC(C2=CC(=C(C=C2)O)C(=O)N)O.Cl
- Other CAS numbers recorded
- 72487-34-4
- PubChem CID
- 71412
Also known as
Labetalol hydrochloride · Labetalol HCL · Labrocol · Ibidomide hydrochloride · Labetalol Hydrocloride · Hydrochloride, Labetalol · Labetalol HCl in Dextrose · Labetalol HCl in Sodium Chloride
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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