API reference
Leflunomide
- CAS number
- 75706-12-6
- Molecular formula
- C12H9F3N2O2
- Molecular weight
- 270.21 g/mol
About this molecule
Leflunomide is a monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide. It has a role as an antiparasitic agent, a non-steroidal anti-inflammatory drug, an antineoplastic agent, an immunosuppressive agent, an EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor, a tyrosine kinase inhibitor, a prodrug, a hepatotoxic agent, an EC 1.3.98.1 [dihydroorotate oxidase (fumarate)] inhibitor and a pyrimidine synthesis inhibitor. It is a monocarboxylic acid amide, a member of isoxazoles and a member of (trifluoromethyl)benzenes.
Source: ChEBI, via PubChem.
Identifiers
- IUPAC name
- 5-methyl-N-[4-(trifluoromethyl)phenyl]-1,2-oxazole-4-carboxamide
- InChIKey
- VHOGYURTWQBHIL-UHFFFAOYSA-N
- SMILES
- CC1=C(C=NO1)C(=O)NC2=CC=C(C=C2)C(F)(F)F
- PubChem CID
- 3899
Also known as
leflunomide · Arava · Leflunomida · Leflunomidum · Repso · leflunomide medac · HWA-486 · Leflunomide teva
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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