API reference

LEVALBUTEROL HCl

CAS number
50293-90-8
Molecular formula
C13H22ClNO3
Molecular weight
275.77 g/mol
LEVALBUTEROL HCl — 2D structure
2D structure (PubChem)

About this molecule

Levalbuterol Hydrochloride is the hydrochloride salt form of levalbuterol, a relatively selective sympathomimetic beta-2 adrenergic receptor agonist with bronchodilator activity. Levalbuterol hydrochloride binds to beta-2 adrenergic receptors in bronchial smooth muscle and activates intracellular adenyl cyclase, thereby increasing the production of cyclic-3', 5'-adenosine monophosphate (cAMP). Increased cAMP levels lead to the activation of protein kinase A, which inhibits the phosphorylation of myosin and lowers intracellular ionic calcium concentrations, resulting in relaxation of bronchial smooth muscles. The increased cyclic AMP concentrations also inhibit the release of inflammatory mediators from mast cells.

Source: NCI Thesaurus (NCIt), via PubChem.

Identifiers

IUPAC name
4-[(1R)-2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol;hydrochloride
InChIKey
OWNWYCOLFIFTLK-YDALLXLXSA-N
SMILES
CC(C)(C)NC[C@@H](C1=CC(=C(C=C1)O)CO)O.Cl
PubChem CID
123601

Also known as

Levalbuterol hydrochloride · Levalbuterol HCl · Xopenex · Levosalbutamol Hydrochloride · (-)-Salbutamol hydrochloride · Albuterol hydrochloride, r- · Albuterol (r)-form hydrochloride · Levalbuterol Inhalation Solution

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