API reference
LEVALBUTEROL HCl
- CAS number
- 50293-90-8
- Molecular formula
- C13H22ClNO3
- Molecular weight
- 275.77 g/mol

About this molecule
Levalbuterol Hydrochloride is the hydrochloride salt form of levalbuterol, a relatively selective sympathomimetic beta-2 adrenergic receptor agonist with bronchodilator activity. Levalbuterol hydrochloride binds to beta-2 adrenergic receptors in bronchial smooth muscle and activates intracellular adenyl cyclase, thereby increasing the production of cyclic-3', 5'-adenosine monophosphate (cAMP). Increased cAMP levels lead to the activation of protein kinase A, which inhibits the phosphorylation of myosin and lowers intracellular ionic calcium concentrations, resulting in relaxation of bronchial smooth muscles. The increased cyclic AMP concentrations also inhibit the release of inflammatory mediators from mast cells.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 4-[(1R)-2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol;hydrochloride
- InChIKey
- OWNWYCOLFIFTLK-YDALLXLXSA-N
- SMILES
- CC(C)(C)NC[C@@H](C1=CC(=C(C=C1)O)CO)O.Cl
- PubChem CID
- 123601
Also known as
Levalbuterol hydrochloride · Levalbuterol HCl · Xopenex · Levosalbutamol Hydrochloride · (-)-Salbutamol hydrochloride · Albuterol hydrochloride, r- · Albuterol (r)-form hydrochloride · Levalbuterol Inhalation Solution
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