API reference
Levobupivacaine
- CAS number
- 27262-47-1
- Molecular formula
- C18H28N2O
- Molecular weight
- 288.4 g/mol
About this molecule
Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by AstraZeneca under the trade name Chirocaine. Compared to bupivacaine, levobupivacaine is associated with less vasodilation and has a longer duration of action. It is approximately 13 per cent less potent (by molarity) than racemic bupivacaine.Levobupivacaine is indicated for local anaesthesia including infiltration, nerve block, ophthalmic, epidural and intrathecal anaesthesia in adults; and infiltration analgesia in children. Adverse drug reactions (ADRs) are rare when it is administered correctly. Most ADRs relate to administration technique (resulting in systemic exposure) or pharmacological effects of anesthesia, however allergic reactions can rarely occur. [Wikipedia]
Source: Toxin and Toxin Target Database (T3DB), via PubChem.
Identifiers
- IUPAC name
- (2S)-1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
- InChIKey
- LEBVLXFERQHONN-INIZCTEOSA-N
- SMILES
- CCCCN1CCCC[C@H]1C(=O)NC2=C(C=CC=C2C)C
- Other CAS numbers recorded
- 41148-30-5
- PubChem CID
- 92253
Also known as
Levobupivacaine · (S)-bupivacaine · (-)-bupivacaine · L-(-)-bupivacaine · (2S)-1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide · Levobupivacaina · Novabupi · (S)-1-Butyl-2',6'-pipecoloxylidide
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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