API reference
Levothyroxine sodium
- CAS number
- 55-03-8
- Molecular formula
- C15H10I4NNaO4
- Molecular weight
- 798.85 g/mol
About this molecule
Levothyroxine Sodium is the sodium salt of levothyroxine, a synthetic levoisomer of thyroxine (T4) that is similar to the endogenous hormone produced by the thyroid gland. In peripheral tissues, levothyroxine is deiodinated by 5'-deiodinase to form triiodothyronine (T3). T3 enters the cell and binds to nuclear thyroid hormone receptors; the activated hormone-receptor complex in turn triggers gene expression and produces proteins required in the regulation of cellular respiration; thermogenesis; cellular growth and differentiation; and the metabolism of proteins, carbohydrates and lipids. T3 also exhibits cardiostimulatory effects.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- sodium (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate
- InChIKey
- YDTFRJLNMPSCFM-YDALLXLXSA-M
- SMILES
- C1=C(C=C(C(=C1I)OC2=CC(=C(C(=C2)I)O)I)I)C[C@@H](C(=O)[O-])N.[Na+]
- Other CAS numbers recorded
- 25416-65-3 · 50809-32-0
- PubChem CID
- 23666112
Also known as
Levothyroxine sodium · L-Thyroxine sodium · Euthyrox · Unithroid · levothroid · Levoxyl · Novothyrox · Letter
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