API reference
Linezolid
- CAS number
- 165800-03-3
- Molecular formula
- C16H20FN3O4
- Molecular weight
- 337.35 g/mol
About this molecule
Linezolid is a synthetic antibiotic which is used for the treatment of infections caused by aerobic Gram-positive bacteria. Its effects are bacteriostatic against both enterococci and staphylococci and bactericidal against most isolates of streptococci. Linezolid exerts its antibacterial activity by inhibiting the initiation of bacterial protein synthesis - more specifically, it binds to the 23S ribosomal RNA of the 50S subunit and, in doing so, prevents the formation of the 70S initiation complex which is essential for bacterial reproduction. Linezolid was initially approved in 2000 and was the first member of the oxazolidinone antibiotic class. A second member of this class, [tedizolid], was approved by the FDA in 2014 and is considered generally more effective and tolerable than its predecessor.
Source: DrugBank, via PubChem.
Identifiers
- IUPAC name
- N-[[(5S)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide
- InChIKey
- TYZROVQLWOKYKF-ZDUSSCGKSA-N
- SMILES
- CC(=O)NC[C@H]1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCOCC3)F
- PubChem CID
- 441401
Also known as
linezolid · Zyvox · Linezolidum · U-100,766 · J01XX08 · LINEZOLID IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER · Zyvoxid · Zyvoxam
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
Tell us the grade, the quantity and the market.
Send the molecule or ingredient, the specification and the destination. We reply from Tehran with the questions, the documents and the next step.