API reference
Lisinopril
- CAS number
- 76547-98-3
- Molecular formula
- C21H31N3O5
- Molecular weight
- 405.5 g/mol
About this molecule
Lisinopril Anhydrous is the anhydrous form of the long-acting angiotensin-converting enzyme (ACE) inhibitor lisinopril with antihypertensive activity. Lisinopril, a synthetic peptide derivative, competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Lisinopril also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- (2S)-1-[(2S)-6-amino-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]hexanoyl]pyrrolidine-2-carboxylic acid
- InChIKey
- RLAWWYSOJDYHDC-BZSNNMDCSA-N
- SMILES
- C1C[C@H](N(C1)C(=O)[C@H](CCCCN)N[C@@H](CCC2=CC=CC=C2)C(=O)O)C(=O)O
- PubChem CID
- 5362119
Also known as
lisinopril · Prinivil · Zestril · Lisinopril anhydrous · Lysinopril · Carace · Novatec · Lisinoprilum
Related entries in the range
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