API reference

Lorazepam

CAS number
846-49-1
Molecular formula
C15H10Cl2N2O2
Molecular weight
321.2 g/mol
Lorazepam — 2D structure
2D structure (PubChem)

About this molecule

Lorazepam is only found in individuals that have used or taken this drug. It is a benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent. [PubChem]Lorazepam binds to an allosteric site on GABA-A receptors, which are pentameric ionotropic receptors in the CNS. Binding potentiates the effects of the inhibitory neurotransmitter GABA, which upon binding opens the chloride channel in the receptor, allowing chloride influx and causing hyperpolerization of the neuron.

Source: Toxin and Toxin Target Database (T3DB), via PubChem.

Identifiers

IUPAC name
7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-1,4-benzodiazepin-2-one
InChIKey
DIWRORZWFLOCLC-UHFFFAOYSA-N
SMILES
C1=CC=C(C(=C1)C2=NC(C(=O)NC3=C2C=C(C=C3)Cl)O)Cl
PubChem CID
3958

Also known as

lorazepam · Ativan · Temesta · Loraz · Wypax · Almazine · Anxiedin · Lorabenz

Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.

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